| 1950 | Osaka Vacuum, Ltd. is established in Osaka. Started manufacturing Oil-sealed Rotary Vacuum Pumps. |
| 1959 | Started manufacturing Roots Vacuum Pumps. |
| 1962 | Opened the Sakai Factory. |
| 1971 | Manufactured Turbo Molecular Pump (TMP) for the first time in Japan, T650A (Awarded 1st Vacuum Technology Award in 1976 for production of TMP in Japan). |
| 1972 | Opened the Hachioji Factory. |
| 1980 | Manufactured the largest steam Ejector for degassing (I.D. 2 m) in Japan. |
| 1981 | Manufactured the Large Scale Cryo Panel for the "Heriotron E" plasma experimental equipment in Kyoto University. |
| 1982 | Manufactured a Vacuum System for the Experimental Nuclear Fusion Reactor, JT60, for the Japan Atomic Energy Research Institute. |
| 1983 | Manufactured the Compound Molecular Pump (CMP), TG550 and its series. (Awarded the 10th Vacuum Technology Award (1985) and the JSME Medal for New Technology (1986), both for development of the CMP.) |
| 1985 | Manufactured the Magnetically Suspended CMP, TG600M, and its series. |
| 1988 | Opened the Nabari Factory. |
| 1991 | Opened the California Office in San Jose, CA, USA. |
| 1993 | Manufactured the Magnetically Suspended CMP for XHV, TG1121M, which reached 10-10Pa (Awarded the 20th Vacuum Technology Award (1995) for developing the MS CMP for XHV). |
| 1996 |
Formed alliance with Cutes Corporation (Taiwan) for sales and repair & support of TMP. Opened Seoul Office in Seoul, Korea. Nabari Factory received ISO9002 certification. |
| 1998 | Formed alliance with Shin Won Precision Co. (currently Shin Won Tech. Co., Ltd., Korea) for repair & support of TMP. Developed the Dry Vacuum Pump, DSP80. Hachioji Factory received ISO9001 certification. |
| 1999 |
Formed alliance with Sterling SIHI GmbH (Germany) for Dry Vacuum Pump business. Manufactured Any orientation type TMP, TG-F Series. |
| 2000 | The 50th anniversary of the establishment. |
| 2001 | Established Shanghai Osaka Vacuum in Shanghai, China. Manufactured the MS CMP for reaction product, the TG-MI Series. |
| 2002 | Opened the Shanghai Office. Manufactured the Full-digital type MS CMP. |
| 2003 | Sakai Factory received ISO9001 certification. |
| 2004 | Manufactured the Ultra-Low Vibration MS CMP, the TG-ML Series. |
| 2005 | Established Osaka Vacuum U.S.A., Inc. (California, USA) Shanghai Osaka Vacuum received ISO9001 certification (0105Q14285R0S/3100) |
| 2006 | Received ISO14001 certification (JQA: EM5143) Manufactured the Ultra-high Vacuum MS CMP, the TG-MU Series. Manufactured the Radiation-hardened MS CMP, the TG-MR Series. |
| 2007 |
Formed alliance with Shikoku Taiyo Nippon Sanso Co., Ltd. for sales and consignment operation. Manufactured the CMP for Analysis and Measurement Systems, the TG70F. |
| 2008 | Manufactured the CMP for Analysis and Measurement Systems, the TG240F. |
| 2009 | Manufactured the Compact Dry Vacuum Pumps DSP series. |
| 2010 | Formed alliance with three companies (Azuma Technos Co., Ltd. , Kyushu Keisokki Co., Ltd. , and Todoroki Sangyo Co., Ltd.) for sales. |